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The results of a study by Poggioli et al [64] revealed that chronic administration of DEX was associated with decreased weight gain, which was attributed to its ability to accelerate fatty acid oxidation, and decrease brown adipose tissue thermogenesis and the activity of uncoupling protein-1 mRNA[64]

Data are presented as the mean SEM

Changes in aminotransferases suggestive of hepatocellular pattern liver injury have been observed as early as a few hours after initial statin exposure to as late as 8 months after initiation

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M., & Aronne, L